A new fertility drug, originally developed to prevent the recurrence of breast cancer, is 30 percent more effective in helping some women become pregnant than one used for more than 40 years, new research shows.
For a study published in the New England Journal of Medicine, researchers at seven different academic centers recruited 750 couples to compare the long-used fertility drug clomiphene citrate, commonly called clomid, to letrozole.
Of the 376 women who were given clomid, 72 became pregnant and gave birth. Of the 374 women who took letrozole, 103 gave birth.
“Letrozole works better, has about the same cost, has fewer side effects, and has a slightly lower twin rate than clomid,” says Gregory Christman, director of the division of reproductive endocrinology and infertility at University of Florida.